A research team from Guangzhou Medical University in China achieved an unprecedented scientific breakthrough by transplanting a genetically modified pig lung into the body of a brain-dead human. According to a study published in Nature Medicine, the transplanted lung functioned for nine full days (216 hours) without immediate immune rejection, a milestone considered a “revolutionary step” in organ transplantation. The success is attributed to genetic modifications made to the pig to reduce immune rejection risks. Previous attempts with pig hearts and kidneys did not yield similar results for lungs, which are more sensitive due to direct exposure to external air. Despite the optimism, scientists emphasize that significant medical challenges remain before clinical trials on living patients can proceed, including managing high blood flow and long-term immune rejection risks. This advancement could open new horizons in addressing the global shortage of human organs if future research overcomes remaining obstacles.